Supplementary Figure 19 : Defining MAFF/MAFK+ cCREs

Supplementary Figure 19 | Defining MAFF/MAFK+ cCREs

a, Bar plot depicting the percentage of MAFF/MAFK+ cCREs in K562 belonging to each cCRE class. b, Bar plot depicting the percentage of K562 low chromatin accessibility (CA) cCREs (gray bar in a) belonging to each cell type-agnostic class. c, Bar pot as defined in a for MAFF/MAFK+ cCREs in HepG2. d, Bar plot as defined in b in HepG2. e, Venn diagram depicting the overlap of MAFF/MAFK+ cCREs in K562 (pink) and HepG2 (green). f, Venn diagram depicting the overlap of low CA MAFF/MAFK+ cCREs in K562 (pink) and HepG2 (green). g, Density plot of STARR scores for MAFF/MARK+ cCREs (gold) compared to a background of all cCREs (black). P-value corresponds to a two sided Wilcoxon rank sum test. h, Nested violin-boxplots showing gene expression in K562 cells for the nearest gene of MAFF/MAFK+ cCREs with low CA in K562 versus genes near other low CA cCREs in K562. P-value corresponds to a two sided Wilcoxon rank sum test.