Density scatter plots showing the latent dimensions of cCRE sequence projected onto two dimensions by UMAP from variational autoencoders trained on three cell lines, K562 (top pink), HepG2 (middle green), and HCT116 (bottom olive). All promoter and enhancer cCREs are shown in column one followed by promoter (column 2) proximal enhancer (column 3), distal enhancer (column 4) and CA-H3K4me3 cCREs (column 5), in subsequent columns.